A British research team was published in a recent issue of the journal of immunology, according to published papers they developed a monoclonal antibody, it has been verified by the experimental model, combined with interferon, the antibody can be effective against tuberculosis infection. The researchers believe that the results help scientists develop new TB treatment. The research team from the university of Dundee, king's college London and st George's university of London institute researchers. They developed the monoclonal antibody is A class A immunoglobulin (lgA), belongs to the homogeneity of antibodies, identification of mycobacterium tuberculosis.
It does this by binding mycobacterium tuberculosis bacteria, triggering the body's immune response, so as to prevent the spread of bacterial growth. Paper said, despite monoclonal antibody has been widely used in the treatment of cancer and inflammatory diseases, but this is the first study showed that it can be used to treat tuberculosis.Immunoglobulin is very important in the human body immune effector molecules, due to the different structures can be divided into IgA, IgD, IgE, IgG and IgM five categories. According to the researchers, is A kind of immunoglobulin to make it easier to fight TB bacteria. Though even before the actual clinical application to a lot of research, but the discovery allowed scientists to develop new TB treatment method is a step closer.
Tuberculosis is one of the major public health problems facing humanity, the world each year about 2 million people died of the disease, the British in 2010, the number of tuberculosis cases has reached a high in ten years. Although due to a variety of antibiotics and prevention drugs produce tuberculosis cases around the world once, but the resulting, tuberculosis strains multidrug resistance is becoming more and more obvious, developed new methods to prevent and control the disease becomes extremely urgent.
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Posted at 2014/08/13 14:24:29 | |
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