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2014年09月24日 イイね!

Circadian rhythms persist without transcription in a eukaryote

Circadian rhythms are ubiquitous in eukaryotes, and coordinate numerous aspects of behaviour, physiology and metabolism, from sleep/wake cycles in mammals to growth and photosynthesis in plants1, 2. This daily timekeeping is thought to be driven by transcriptional–translational feedback loops, whereby rhythmic expression of ‘clock’ gene products regulates the expression of associated genes in approximately 24-hour cycles. The specific transcriptional components differ between phylogenetic kingdoms3.

Monoclonal antibody is the most commonly used research tool in biology and modern medicine research field, obtaining high-quality antibodies is usually the first step to study protein function. CUSABIO engaged in the professional customization services for monoclonal antibody and polyclonal antibody production and they also provide high quality antibody custom service . we have many experts who have studied in molecular biology, immunology fields for many years. We have first-class antibody preparation staff, developed antibody production equipment, advanced antibody preparation technologies.

There are rabbits, guinea pigs, goats and others animal species for your choice . Cusanio currently has developed more than 5000 antibodies , which can meet the biological research and development demands .If you can not find satisfied antibody from http://www.cusabio.com/pro_28.html , you can order the antibody custom service from us . We will produce the antibody according to your requirement . And you don’t need to worry about the custom service fees , we ensure provide you with the best competitive price compared with others suppliers .
Posted at 2014/09/24 14:18:13 | コメント(0) | トラックバック(0) | antibody | 日記
2014年08月13日 イイね!

A monoclonal antibody can prevent pulmonary tuberculosis infection

A British research team was published in a recent issue of the journal of immunology, according to published papers they developed a monoclonal antibody, it has been verified by the experimental model, combined with interferon, the antibody can be effective against tuberculosis infection. The researchers believe that the results help scientists develop new TB treatment. The research team from the university of Dundee, king's college London and st George's university of London institute researchers. They developed the monoclonal antibody is A class A immunoglobulin (lgA), belongs to the homogeneity of antibodies, identification of mycobacterium tuberculosis.

It does this by binding mycobacterium tuberculosis bacteria, triggering the body's immune response, so as to prevent the spread of bacterial growth. Paper said, despite monoclonal antibody has been widely used in the treatment of cancer and inflammatory diseases, but this is the first study showed that it can be used to treat tuberculosis.Immunoglobulin is very important in the human body immune effector molecules, due to the different structures can be divided into IgA, IgD, IgE, IgG and IgM five categories. According to the researchers, is A kind of immunoglobulin to make it easier to fight TB bacteria. Though even before the actual clinical application to a lot of research, but the discovery allowed scientists to develop new TB treatment method is a step closer.

Tuberculosis is one of the major public health problems facing humanity, the world each year about 2 million people died of the disease, the British in 2010, the number of tuberculosis cases has reached a high in ten years. Although due to a variety of antibiotics and prevention drugs produce tuberculosis cases around the world once, but the resulting, tuberculosis strains multidrug resistance is becoming more and more obvious, developed new methods to prevent and control the disease becomes extremely urgent.

Cusabio antibodies production adopt recombinant protein or natural protein preparation, compared with the peptide antibodies, have the better affinity and specificity to natural protein, and can identify antigen sites more , having wider application . To buy high quality monoclonal antibody products ,please come to Cusabo , you can also visit our website http://www.cusabio.com/pro_21.html . More details at http://www.cusabio.com/Native_Protein-118597/.
Posted at 2014/08/13 14:24:29 | コメント(0) | トラックバック(0) | antibody | 日記
2014年07月16日 イイね!

Monoclonal antibodies therapeutic development trends

Antibodies are proteins in the immune system that help the body defend against foreign invasion, particularly from pathogens and toxins. As such, a human-engineered therapeutic monoclonal antibody (mAb) is protein derived from the immune system through recombinant DNA technology that has the ability to combine specifically with a target protein that plays a role in a disease process. With this unique ability to specifically target diseased cells while leaving healthy cells unaffected, monoclonal antibodies can serve to diagnose and treat a wide range of medical conditions.

Areas such as breast cancer therapy have benefited greatly since the advent of drugs like Herceptin (trastuzumab) that interferes with the HER2/neu receptor. Indeed, the field of therapeutic monoclonal antibodies potentially has far-reaching and paradigm-shifting implications for biology, drug discovery, and medical treatment of disease. The discipline has already yielded discoveries that have been used for drug delivery and diagnostic purposes, and other exciting new therapeutic applications.

Therapeutic Monoclonal Antibodies Markets report reviews the market for medical products based on emerging therapeutic monoclonal antibodies. It defines the dollar volume of sales in the U.S. and worldwide, and it analyzes the factors that influence the size and the growth of the market segments. The study goes on to discuss in detail the trends that have developed which have stimulated this market and surveys many of the companies marketing, manufacturing or developing monoclonal antibodies therapies.

Monoclonal antibodies for non-therapeutic purposes--used primarily in life science and research applications--are not discussed in this review. Cusabio is a reliable antibody supplier , the monoclonal antibody are produced by the professionals who have worked on antibody for many years . Concentrate on antibody , Cusabio has developed series of antibody products , including diagnostic and polyclonal antibody products . They provide antibody products for the customers all over the world . For more Cusabio antibody information , visit here http://www.cusabio.com/pro_12.html.
Posted at 2014/07/16 15:59:56 | コメント(0) | トラックバック(0) | antibody | 日記

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Advantages and limitations of monoclonal antibodies  
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2014/10/13 18:17:25
Monoclonal antibodies therapeutic development trends 
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Scientists successfully isolate the protein that can control brain activity 
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