The monoclonal antibody is produced by a B , and the gene sequence of monoclonal antibodies are same. And the monoclonal antibody just identify single epitope. While polyclonal antibody is a mixture antibodies, all animals can be identified in vivo B cell secretion of the antigen . Polyclonal antibody can recognize different epitopes of the antigen.
Monoclonal and polyclonal antibodies have their own advantages and limitations, and only to have a thorough understanding of the advantages and limitations , can you correctly choose the right antibody according to the various applications . In the view of monoclonal antibodies , the major advantages and the limitations include three points . Firstly ,the hybridomas can survive and passaged in vitro "permanent", as long as mutation cell line does not occur, and at the same time it will continuously produce high specificity & high homogeneity antibodies .
Secondly , even with a relatively impure antigen, a lot of highly specific, homogeneous antibodies can be produced in this situation . Thirdly , monoclonal antibody is suitable for immunological analysis method , such as ELISA and IRMA technologies . And with the methods , the "unlimited" in homogeneous antibodies are available .Finally , due to the high specificity and biological function of a single monoclonal antibody , it can be used for in vivo Radioimmunoimaging and immune-directed therapy.
Bioabb engaged in antibody production for many years and now it has become a global famous antibody supplier . Bioabbb located in Wuhan Hi-tech Medical Devices Park , experienced more than 5 years development , established a series of antibody development platforms . Besides , Bioabb all proficient in a series of antibody technologies . Combined with their professional antibody researchers , they have produced more than 5000 antibodies , include monoclonal antibody, olyclonal antibody , secondary antibody and others species antibodies . If you are in need of high quality antibodies, Bioabb antibodies are best choice for you , visit Bioabb at
http://www.bioabb.com/categories/Antibody/Monoclonal-Antibody/ .
Posted at 2014/10/13 18:13:56 | |
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