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2014年10月23日 イイね!

Scientists uncover the mystery of histone label

Researchers carefully observed the tropical flies as well as parasitic which lays in tropical flies , revealing an incredibly complex network of interactions . If there are no advanced molecular technologies , some of these interactions are still not be found . This complex network proposed a question that how the related species interact each other . And it also indicates that the interactions between the species are challenged .

Now, a new study done by YannickJacob and his colleagues showed that the interaction between Arabidopsis and ATXR6 as well as a histone variants calls H3.1 maintain the a key H3K27me1 mark in Arabidopsis ; ATXR5 and ATXR6 are two enzymes to modify histone , while histone is a protein which can put DNA into heterochromatin .In plants, a special label which calls H3K27me1on heterochromatin - or on compact arrangement DNA must be conservative when cells division , only by this , can its daughter cells accept similar organization DNA.

Researchers figured out the crystal structure of ATXR5 , which can form a complex with H3.1 peptide , while it shows that why ATXR5 enzymes are trend to rely the replicated H3.1 variants compared with variant H3.3 which do not depend on the replication . Their research confirmed that how histone variants control the enzymes which can re-shape the heterochromatin in the nucleus so that to direct gene expression changes .

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Posted at 2014/10/23 12:52:12 | コメント(0) | トラックバック(0) | 日記

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