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Researchers from the Fred Hutchinson Cancer Center in Seattle, USA, etc. through studies , showing that patients receiving chest radiation therapy to treat Wilms tumor may enhance the risk of breast cancer due to the exposure to radiation . Related research results were published in international magazine《cancer》. This research reveals cancer screening guidelines should perhaps be re-evaluated in order to promote the early diagnosis of Wilms tumor patients and prompt risk of breast cancer

Wilms' tumor is a rare childhood kidney cancer, which can spread to the lungs, when the cancer spreads, patients need 12-14 gray degree radiation therapy; In order to clarify whether the radiation exposure may affect the risk of suffering from breast cancer, researchers Norman Breslow and colleagues conducted research on 2500 young women in their childhood with wilms tumor radiotherapy . In the surviving female patients who received chest radiation , more than 20% of individuals suffering from breast cancer at the age of 40 , while the patients with wilms tumor who didn’t receive radiotherapy suffer from the breast cancer only is 0.3% ; patients who accept abdominal radiation therapy to treat wilms' tumor , the risk of suffering from breast cancer is just 4% .


Dr. Breslow said that if the patient's breast tissue received 20 or more gray radiation therapy, early screening should be added to the childhood Cancer Survivors , which will be very critical. for revealing the risk of suffering from breast cancer as well as early treatment for these individuals . The researchers also pointed that Wilms' tumor patients with high risk need to check x-ray and the breast MRI . This new research provides a new method to treat breast cancer . And in the future researchers also need to overcome many obstacles to achieve greater success .

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The first step to implement appropriate treatment is accurate diagnosis - even in the case of incurable situation , which is very important. One of the developers of PhenIX diagnostics Peter Robinson said: "At least, it provides assurance , disease is not caused by their own." PhenIX represents "Phenotypic Interpretation of eXomes". In the past, these disease just can be genetic analyzed . However, this is not always sufficient to accurately detect the disease. All the detected problem is that individual differences in patient makes diagnosis becomes very difficult , we must find important differences from millions genetic variation of everyone inherent norms .

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