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Scientists, integrate the next-generation sequencing technology (NGS), bioinformatics and clinical data to develop an effective diagnostic procedures , which can significantly increase the diagnosis prospects for affected patients. The program was freely provided to relevant medical care and can be used immediately.

The first step to implement appropriate treatment is accurate diagnosis - even in the case of incurable situation , which is very important. One of the developers of PhenIX diagnostics Peter Robinson said: "At least, it provides assurance , disease is not caused by their own." PhenIX represents "Phenotypic Interpretation of eXomes". In the past, these disease just can be genetic analyzed . However, this is not always sufficient to accurately detect the disease. All the detected problem is that individual differences in patient makes diagnosis becomes very difficult , we must find important differences from millions genetic variation of everyone inherent norms .

To solve this problem, scientists in Berlin developed an innovative diagnostic procedures. In contrast with the conventional diagnostic tests, PhenIX combined genetic abnormalities analysis with the clinical manifestations. In the first step, they carry out a specific search to find about 3000 known genes which will lead to disease . In order to find which genes they are, the scientists systematically searched publicly available databases, and created a list of known genetic defects. In the next step , the major doctor scans the Human Phenotype Ontology , a database developed by Charité , so as to search for the symptoms of the patients . Finally the scientists conducted a clinical experiment , they detected a group of patients , found that with the method of PhenIX , they can find out their exact cause .

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Sepsis is a syndrome caused by infection, which can lead to organ failure, and up to five million deaths each year. There are around 18 million cases of sepsis each year. The new discovery will reduce the confirming time that whether the patient is suffering from sepsis, it will also increase the efficacy of their feedback. Recently, studies of University of British Columbia have developed a new test that can help doctors predict whether a patient will suffer from severe sepsis within an hour, so they can immediately begin to treat sepsis .

"Once we have discovered a genetic marker , which is related to the diagnosis of sepsis al well as the following organ failure ", said Bob Hancock ," once the patients went to emergency room , we can test this gene marker" , usually it will takes 24-48 hours to diagnose this kind of disease , but with this new test, doctors can immediately begin treating patients. The latest gene labeling test is published in the magazine of 《EBioMedicine》, the test just need one hour to diagnose 96% of patients in the early stages of sepsis .

The results also show a misunderstanding of the disease. Until now, sepsis is still considered as an inflammatory disease, more than 30 kinds of anti-inflammatory are ineffective to treat sepsis in clinical experiment , Hancock as well as his colleagues found a genetic marker associated with recombinant cell immune inhibitors , while the special recombinant cell immune inhibitor is a not good method to treat inflammatory sepsis .

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Anybody who had invested much more time in seeking to increase more muscle mass, he or she had possibly realized that it really is important to eat significant amount of bodybuilding protein in order to build significant muscle increases. Both bobybuilders as well as diet advisors are likely to advise of ingesting around one-two grams for every pound of the bodyweight day-after-day. The fact is, numerous protein food products are usually filling, dense, costly and also aggravating. Another issue with these items is that they are usually not created for the tummy and they are difficult on the pocket. Nonetheless, there are precise ways that people today need to comprehend before combining the bodybuilding protein in the diet. Are you aware that eating egg whites can assist in creating lean muscle groups? This could be unacceptable but unlike the egg yolks, egg whites include the same taste. Moreover, if eggs are ordered pre-separated in a package, these are truly pasturized.

Quite a few health conscious people have discovered that the easiest and greatest way to take in fresh egg whites is combine them having fruits and veggies and some sugar. The shake will mix quickly and based on how constant whites or even boxes of eggs utilized, the physique can effortlessly take in around 50 to 100 grams of beneficial bodybuilding protein.in. Though canned tuna is not a well known variety of appetizer that many people today will eat, it's actually a affordable and packed-food bodybuilding protein. Make certain to pick the light chunk tuna, which is thought to be a cheaper and really easy to consume food stuff alternative. Someone may normally eat up around 25gms of protein without wasting over one dollar.

One particular solution to eat a considerable amount of tuna would be to take in really huge slices, as well as be guaranteed to munch them correctly and do not forget to drink plenty of drinking water, even if a few individuals usually do not truly value the flavor but the rewards are optimum. If you don’t want to get protein by eating , you can choose to take some protein drugs .

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Recently, research from the University of Montreal and other agencies developed a diabetes therapy by controlling the patients’ Neu1 level . And the related research performance published in the magazine of《Diabetes》.Portion of insulin resistance in patients with type II diabetes mainly are caused by lacking of certain protein , while this protein has no connection with diabetes . Type II diabetes accounted for 90% of worldwide diabetic population , affecting the health of 2.5 million Canadians , it will takes 15 billion yuan to treat diabetes every year in Canada . The researchers explained that they found Neuraminidase 1 can adjust sialic acid on the surface of cells to realize the opening or closing of body cells absorbing sugar .

Researchers are now trying to look for a method to restore Neu1 level and function . If they can remove sialic acid residues from the surface of cells , they will make the insulin receptor were suitable for carbohydrate absorption. This may give doctors an idea to reduce the use of insulin therapy as well as reduce the prevalence of diabetes.

Usually , diabetes treatment are traditional antibody therapies , this new discovery bring diabetes patients back to life , providing a potential treatment for diabetes . Bioabb is a world famous biotechnology company , focus on high quality antibody production and custom service . Bioabb current antibodies include monoclonal antibodies , polyclonal antibodies , secondary antibodies and others antibodies. Bioabb antibodies are widely used in modern medicine development and clinical disease treatment . Bioabb antibodies are very popular in the antibody market for the high efficiency and good quality . If you want to know more details info about Bioabb antibody , visit http://www.bioabb.com/categories/Antibody/ .

Researchers carefully observed the tropical flies as well as parasitic which lays in tropical flies , revealing an incredibly complex network of interactions . If there are no advanced molecular technologies , some of these interactions are still not be found . This complex network proposed a question that how the related species interact each other . And it also indicates that the interactions between the species are challenged .

Now, a new study done by YannickJacob and his colleagues showed that the interaction between Arabidopsis and ATXR6 as well as a histone variants calls H3.1 maintain the a key H3K27me1 mark in Arabidopsis ; ATXR5 and ATXR6 are two enzymes to modify histone , while histone is a protein which can put DNA into heterochromatin .In plants, a special label which calls H3K27me1on heterochromatin - or on compact arrangement DNA must be conservative when cells division , only by this , can its daughter cells accept similar organization DNA.

Researchers figured out the crystal structure of ATXR5 , which can form a complex with H3.1 peptide , while it shows that why ATXR5 enzymes are trend to rely the replicated H3.1 variants compared with variant H3.3 which do not depend on the replication . Their research confirmed that how histone variants control the enzymes which can re-shape the heterochromatin in the nucleus so that to direct gene expression changes .

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