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Researchers have invented method to produce a light-sensitive membrane protein,which is capable to manipulate neural activity in test tube . This latest research performance was published in “Nature - Methodology ” .By using the light-sensitive protein and the corresponding light stimulation , neuronal activity can be controlled. To meet the demands of gene research and gene therapy , the scientists are always try their best to design a novel light-sensitive protein which have a better neuron controlling ability .

Ernst Bamberg as well as his colleagues developed a protein engineering strategy , integrate the gene of two kinds of light-sensitive microbial protein to produce hybrid protein . This method make sure the colocalization and equal expression of the proteins in cells , so as to exactly activate or inhibit specific neuronal , which also contribute to studying brain functions and behavior.

The engineered protein developed by Bamberg and his colleagues can respond to a wider range of the spectrum. The light-sensitive protein developed by Ernst Bamberg can use "white" light to activate nerve cells, at the same time it is possible to apply to the ongoing gene therapy to restore vision. However, researchers also need to test this mutant protein on model animal .

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Researchers have invented method to produce a light-sensitive membrane protein,which is capable to manipulate neural activity in test tube . This latest research performance was published in “Nature - Methodology ” .By using the light-sensitive protein and the corresponding light stimulation , neuronal activity can be controlled. To meet the demands of gene research and gene therapy , the scientists are always try their best to design a novel light-sensitive protein which have a better neuron controlling ability .

Ernst Bamberg as well as his colleagues developed a protein engineering strategy , integrate the gene of two kinds of light-sensitive microbial protein to produce hybrid protein . This method make sure the colocalization and equal expression of the proteins in cells , so as to exactly activate or inhibit specific neuronal , which also contribute to studying brain functions and behavior.

The engineered protein developed by Bamberg and his colleagues can respond to a wider range of the spectrum. The light-sensitive protein developed by Ernst Bamberg can use "white" light to activate nerve cells, at the same time it is possible to apply to the ongoing gene therapy to restore vision. However, researchers also need to test this mutant protein on model animal .

As a world famous biotechnology company , Bioabb is a worth relying on protein supplier , experienced years development , Bioabb now become a strong comprehensive biotechnology company , offering a series of high quality to serve biology and modern medicine research and development . Besides owning professional R & D team of small molecule antigen synthesis and advanced experimental facilities, we also cooperate with Wuhan University and Huazhong Agricultural University, and employ experienced researchers to be our technical consultants. Bioabb forever development aim is to meet the increasing demands for high quality proteins , your satisfaction is Bioabb development motivation . For more details info , please visit native protein

Recently, researchers from McGill University in England found that the main chemical components of salt - sodium , is a major neurotransmitter receptor specificity "switch." The receptor is known as kainate (kainate-receptor), which is associated with a number of diseases such as epilepsy and neuropathic pain . Related study published in the "Nature Structural & molecular BioLogy"

The balance of kainate receptor activity is the key to maintaining the normal brain functions. Under conditions such as epilepsy, kainate activity is considered to be excessive. Thus, the drugs that closed the activity of kainate are expected beneficial . The researchers said that, over past decades, the assumed brain receptor "switches" are considered to locate in the neurotransmitter binding site. Now scientists have discovered a completely separate sites, the sodium combined with a single atom , controlling kainate receptors on and off.

Sodium switch is special for kainate receptor , indicating aimed to stimulate the current switch drugs are not functional in others parts of the brain . Researchers believed that : Now that we have known how to stimulate kainate receptor, then it should be possible to design drugs to turn off the receptors. Researchers are trying to use computer simulation to predict how sodium affects the kainate receptors.

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People may have experienced falling into asleep after dinner . British researchers say it may be related to food ingredients, those sugary foods are more likely to make people drowsy, but the food contains more protein help to keep awake.Researchers from University of Cambridge and other institutions published a new issue in the journal "Neuron" , they reported said, they monitor the changes of a special protein in their brain when the mice intakes various food . This kind of cell can secrete a substance called "Hypothalamic secretin" , which contribute to stimulating the body to keep awake and active state

The researchers found that when mice foods contain a large amount of sugar, the glucose would impede the function of these cells to reduce the number of hypothalamic hormone secretion , allowing easier trapped mice. While if the food contains more protein, amino acids which produced by proteins , resulting in the opposite effect , contribute to make the mice stay awake . Researchers Dennis Buldakov said: "This discovery shows that we might be able to help yourself to stay awake as well as to fall asleep by choosing foods, such as when you want to stay awake, you need not smear jam on bread, instead eating some eggs is a good choice for you to stay awake . "

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Washington University in St. Louis's developmental biologist Ichiro Imai (sound) found a protein over expressed SIRT1 in the brains of mice can delay the beginning of aging , so as to achieve the effect of prolonged youth. Foreign media said that if there is the opportunity to choose, Marjory people are willing to make himself eternal youth, immortality. It can extend the life of the suspect A protein which was suspected whether it is able to extend life time in the past years has recently been shown that it really can extend human life .

The research shows the structure of the so-called "longevity" protein SIRT1. This protein works in the brain can delay the aging beginning , but not delay the aging process,, thus prolonging the youth, injecting additional vitality for for the individual's life cycle

The researchers trained a mice which can release a higher SIRT1 than normal levels of SIRT1 in the brain of mice, and found that the life of this creature has been significantly extended. In particular, the research team found that, SIRT1 play an vital role in protecting human body from age-related human skeletal muscle aging , incapacity recession, hypothermia, oxygen consumption reducing and decreased sleep quality .

Report pointed out that this discovery could help researchers to get a better understanding about how to extend the life of other mammals, including humans. If you are wondering how to extend the life length , you can visit http://www.bioabb.com/products/Recombinant-Donkey-Lysozyme-C%28LYZ%29.html . Bioabb offers first class RT-PCR technical service , which can detect the gene expression changes in cells or tissues . Bioabb provides excellent RT-PCR technical service to serve clinical drugs development , and they always try their best to provide high quality service for you . Bioabb provides you with more sensitive, convenient, inexpensive and easy to operate RT-PCR technical service . And you don’t need to worry about the cost of the technical service , Bioabb guarantees provides you with affordable price !