Although the therapy has been greatly improved, but for two adult suffered from acute myeloid leukemia (AML) , there was only one person will survive from it . For 65 years or older, acute myeloid leukemia average survival period of less than one years; but researchers speculate that the incidence of leukemia stem cells may be due, in patients with leukemia stem cells in the body and can not be completely cleared, these leukemic stem cells in patients with relapse is the ultimate cause of death.
Researchers come from Goethe-Universitat Frankfurt am Main researched the drawbacks of acute myeloid leukemia stem cells ,finding a lipoxygenase calls 5-LO , which play an key role in leukemia stem cell survival .Previous studies have found a 5-LO role in inflammatory diseases such as asthma pathogenesis, the researchers Jessica Roos professor said the study, we found that acute myeloid leukemia subgroup of leukemic stem cells might be 5- LO inhibitors effectively selectively attacks, but the phenomenon can be observed in a cell culture model and mouse models of leukemia.
=The researchers said the study provide new research evidence and clues for acute myeloid leukemia treatment . At the latter part of the study , the researchers also revealed the the functions and mechanism of 5-lipoxygenase inhibitors in leukemia stem cell . For more details info you can visit
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Posted at 2014/10/20 14:47:48 | |
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